Composite mantle cell lymphoma and small lymphocytic lymphoma in a lymph node
نویسندگان
چکیده
منابع مشابه
Synchronous interdigitating dendritic cell sarcoma and B-cell small lymphocytic lymphoma in a lymph node.
A gradually enlarging axillary mass in a 79-year-old man was excised. The specimen was processed for light microscopy, immunohistochemical studies, and electron microscopy; gene rearrangement studies were also performed. A diagnosis of an interdigitating dendritic cell tumor of the lymph node and a B-cell small lymphocytic lymphoma occurring in the same anatomic location was made. We found that...
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Here we describe a case of a composite mantle cell lymphoma (MCL) and chronic lymphocytic leukemia/small cell lymphocytic lymphoma (CLL/SLL) with 17p deletion in the MCL. The patient presented with 3 years of progressive lymphocytosis. Cervical lymph node biopsy showed morphologic features of nodular MCL and internodular CLL/SLL, two populations of CD5+ cells by flow cytometry, a t(11;14) trans...
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Composite lymphomas are defined as two unrelated, morphologically and genetically distinct lymphomas occurring at the same point in time within the same tissue or organ. Since their original definition, several composite lymphomas have been reported exclusively based on morphological grounds. However, with the application of immunohistological and molecular biological techniques it has become e...
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BACKGROUND B-cell chronic lymphocytic leukemia/ small lymphocytic lymphoma (B-CLL/SLL) and mantle cell lymphoma (MCL) show many overlapping morphologic and immunophenotyping features, however they have great difference in therapeutic regimens and prognosis. THE AIM OF THE STUDY Is to determine the diagnostic and prognostic role of clinico-pathologic variables, CD23 and Cyclin D1 oncoprotiens ...
متن کاملSmall lymphocytic lymphoma, marginal zone B-cell lymphoma, and mantle cell lymphoma exhibit distinct gene-expression profiles allowing molecular diagnosis.
Non-germinal center small B-cell lymphomas represent a heterogeneous group of non-Hodgkin lymphomas, the most frequent histologic subtypes being small lymphocytic lymphoma (SLL), splenic marginal zone B-cell lymphoma (MZL), and mantle cell lymphoma (MCL). In order to identify genomic signatures specific for each disease, we analyzed 128 primary tumors using high-density microarrays. Several clu...
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ژورنال
عنوان ژورنال: Blood
سال: 2021
ISSN: ['1528-0020', '0006-4971']
DOI: https://doi.org/10.1182/blood.2020009288